G35E (p.Gly35Glu) variant of FGFR1 (P11362)
G35E (p.Gly35Glu) in FGFR1 (P11362) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
G35E (p.Gly35Glu) variant details
- p.Gly35Glu
- NCI-TCGA TCGA novel
- Ensembl rs2150967003
- Variant assessed as somatic; high impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.47
- REVEL 0.29
- CADD 20.70
- PolyPhen-2 0.00
- SIFT 1.00
- UniProt: Variant assessed as somatic; high impact.
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available