W7G (p.Trp7Gly) variant of FGB (Fibrinogen beta chain)
W7G (p.Trp7Gly) in FGB (Fibrinogen beta chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
W7G (p.Trp7Gly) variant details
- p.Trp7Gly
- gnomAD 4-154563037-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.365
- REVEL 0.15
- CADD 22.80
- PolyPhen-2 0.11
- SIFT 0.16
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available