W7C (p.Trp7Cys) variant of FGB (Fibrinogen beta chain)
W7C (p.Trp7Cys) in FGB (Fibrinogen beta chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
W7C (p.Trp7Cys) variant details
- p.Trp7Cys
- gnomAD rs1339198946
- Missense
- Variant Prioritization Score for Impact Estimate 0.28
- REVEL 0.14
- CADD 23.70
- PolyPhen-2 0.01
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available