V25A (p.Val25Ala) variant of FGB (Fibrinogen beta chain)
V25A (p.Val25Ala) in FGB (Fibrinogen beta chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
V25A (p.Val25Ala) variant details
- p.Val25Ala
- TOPMed rs1258637928
- Missense
- Variant Prioritization Score for Impact Estimate 0.191
- REVEL 0.11
- CADD 15.20
- PolyPhen-2 0.00
- SIFT 0.18
- Most common in the East Asian population (allele frequency 2.6e-05)
- Structural context available