T14S (p.Thr14Ser) variant of FGB (Fibrinogen beta chain)
T14S (p.Thr14Ser) in FGB (Fibrinogen beta chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
T14S (p.Thr14Ser) variant details
- p.Thr14Ser
- gnomAD 4-154563058-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.207
- REVEL 0.08
- CADD 20.40
- PolyPhen-2 0.00
- SIFT 0.19
- Most common in the Non-Finnish European population (allele frequency 2.8e-06)
- Structural context available
- Literature evidence available