S8R (p.Ser8Arg) variant of FGB (Fibrinogen beta chain)
S8R (p.Ser8Arg) in FGB (Fibrinogen beta chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
S8R (p.Ser8Arg) variant details
- p.Ser8Arg
- TOPMed rs1194557267
- gnomAD rs1194557267
- Missense
- Variant Prioritization Score for Impact Estimate 0.136
- REVEL 0.02
- CADD 21.40
- PolyPhen-2 0.03
- SIFT 0.04
- Most common in the African/African-American population (allele frequency 6.2e-05)
- Structural context available