S8G (p.Ser8Gly) variant of FGB (Fibrinogen beta chain)
S8G (p.Ser8Gly) in FGB (Fibrinogen beta chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
S8G (p.Ser8Gly) variant details
- p.Ser8Gly
- TOPMed rs1194557267
- gnomAD rs1194557267
- Missense
- Variant Prioritization Score for Impact Estimate 0.128
- REVEL 0.03
- CADD 18.60
- PolyPhen-2 0.01
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available