S6F (p.Ser6Phe) variant of FGB (Fibrinogen beta chain)
S6F (p.Ser6Phe) in FGB (Fibrinogen beta chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
S6F (p.Ser6Phe) variant details
- p.Ser6Phe
- ExAC rs752925190
- gnomAD rs752925190
- Missense
- Variant Prioritization Score for Impact Estimate 0.182
- REVEL 0.09
- CADD 20.50
- PolyPhen-2 0.12
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available