S42G (p.Ser42Gly) variant of FGB (Fibrinogen beta chain)
S42G (p.Ser42Gly) in FGB (Fibrinogen beta chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
S42G (p.Ser42Gly) variant details
- p.Ser42Gly
- TOPMed rs1730130853
- Missense
- Variant Prioritization Score for Impact Estimate 0.121
- REVEL 0.11
- CADD 0.16
- PolyPhen-2 0.00
- SIFT 0.27
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available