R3T (p.Arg3Thr) variant of FGB (Fibrinogen beta chain)
R3T (p.Arg3Thr) in FGB (Fibrinogen beta chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
R3T (p.Arg3Thr) variant details
- p.Arg3Thr
- gnomAD 4-154563026-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.174
- REVEL 0.06
- CADD 22.10
- PolyPhen-2 0.11
- SIFT 0.03
- Most common in the South Asian population (allele frequency 1.3e-05)
- Structural context available
- Literature evidence available