R3K (p.Arg3Lys) variant of FGB (Fibrinogen beta chain)
R3K (p.Arg3Lys) in FGB (Fibrinogen beta chain) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
R3K (p.Arg3Lys) variant details
- p.Arg3Lys
- gnomAD 4-154563021-G-GA
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.417
- CADD 23.40
- Most common in the Non-Finnish European population (allele frequency 9.8e-07)
- Structural context available
- Literature evidence available