M4V (p.Met4Val) variant of FGB (Fibrinogen beta chain)
M4V (p.Met4Val) in FGB (Fibrinogen beta chain) is a missense change. Clinical records from EBI and UniProt describe it as uncertain significance. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
M4V (p.Met4Val) variant details
- p.Met4Val
- ExAC rs767891657
- TOPMed rs767891657
- gnomAD rs767891657
- Uncertain significance
- Missense
- Variant Prioritization Score for Impact Estimate 0.141
- REVEL 0.10
- CADD 14.10
- PolyPhen-2 0.00
- SIFT 0.01
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Population evidence available
- Structural context available