L27* (p.Leu27Ter) variant of FGB (Fibrinogen beta chain)
L27* (p.Leu27Ter) in FGB (Fibrinogen beta chain) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
L27* (p.Leu27Ter) variant details
- p.Leu27Ter
- NCI-TCGA TCGA novel
- Variant assessed as somatic; high impact.
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.577
- CADD 22.70
- UniProt: Variant assessed as somatic; high impact.
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available