L21V (p.Leu21Val) variant of FGB (Fibrinogen beta chain)
L21V (p.Leu21Val) in FGB (Fibrinogen beta chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
L21V (p.Leu21Val) variant details
- p.Leu21Val
- gnomAD 4-154563079-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.206
- REVEL 0.13
- CADD 17.70
- PolyPhen-2 0.25
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available