L20M (p.Leu20Met) variant of FGB (Fibrinogen beta chain)
L20M (p.Leu20Met) in FGB (Fibrinogen beta chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
L20M (p.Leu20Met) variant details
- p.Leu20Met
- gnomAD 4-154563076-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.194
- REVEL 0.18
- CADD 19.40
- PolyPhen-2 0.69
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available