L19S (p.Leu19Ser) variant of FGB (Fibrinogen beta chain)
L19S (p.Leu19Ser) in FGB (Fibrinogen beta chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
L19S (p.Leu19Ser) variant details
- p.Leu19Ser
- gnomAD 4-154563074-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.144
- REVEL 0.05
- CADD 20.40
- PolyPhen-2 0.01
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available