L18P (p.Leu18Pro) variant of FGB (Fibrinogen beta chain)
L18P (p.Leu18Pro) in FGB (Fibrinogen beta chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
L18P (p.Leu18Pro) variant details
- p.Leu18Pro
- gnomAD rs1166051982
- Missense
- Variant Prioritization Score for Impact Estimate 0.441
- REVEL 0.28
- CADD 27.40
- PolyPhen-2 0.82
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.6e-05)
- Structural context available