L12H (p.Leu12His) variant of FGB (Fibrinogen beta chain)
L12H (p.Leu12His) in FGB (Fibrinogen beta chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
L12H (p.Leu12His) variant details
- p.Leu12His
- gnomAD 4-154563053-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.151
- REVEL 0.04
- CADD 18.10
- PolyPhen-2 0.05
- SIFT 0.10
- Population evidence available
- Structural context available
- Literature evidence available