K11E (p.Lys11Glu) variant of FGB (Fibrinogen beta chain)
K11E (p.Lys11Glu) in FGB (Fibrinogen beta chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
K11E (p.Lys11Glu) variant details
- p.Lys11Glu
- ExAC rs756304323
- gnomAD rs756304323
- Missense
- Variant Prioritization Score for Impact Estimate 0.174
- REVEL 0.07
- CADD 21.30
- PolyPhen-2 0.02
- SIFT 0.01
- Most common in the South Asian population (allele frequency 9.9e-05)
- Structural context available