G32D (p.Gly32Asp) variant of FGB (Fibrinogen beta chain)
G32D (p.Gly32Asp) in FGB (Fibrinogen beta chain) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.04 / 1. The record also includes population frequency data and structural context.
G32D (p.Gly32Asp) variant details
- p.Gly32Asp
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.0389
- REVEL 0.03
- CADD 0.00
- PolyPhen-2 0.04
- SIFT 0.28
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 9.4e-07)
- Structural context available