S45T (p.Ser45Thr) variant of FGA (Fibrinogen alpha chain)
S45T (p.Ser45Thr) in FGA (Fibrinogen alpha chain) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data.
S45T (p.Ser45Thr) variant details
- p.Ser45Thr
- gnomAD rs1395097897
- Missense
- Variant Prioritization Score for Impact Estimate 0.264
- REVEL 0.17
- CADD 23.60
- PolyPhen-2 0.99
- SIFT 0.04
- Most common in the East Asian population (allele frequency 2.5e-05)