R35P (p.Arg35Pro) variant of FBXW7 (Q969H0)
R35P (p.Arg35Pro) in FBXW7 (Q969H0) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
R35P (p.Arg35Pro) variant details
- p.Arg35Pro
- 1000Genomes rs199629238
- ExAC rs199629238
- TOPMed rs199629238
- gnomAD rs199629238
- Missense
- Variant Prioritization Score for Impact Estimate 0.322
- REVEL 0.29
- CADD 24.10
- PolyPhen-2 0.33
- SIFT 0.00
- Population evidence available
- Structural context available