R14* (p.Arg14Ter) variant of FBXW7 (Q969H0)
R14* (p.Arg14Ter) in FBXW7 (Q969H0) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.85 / 1. The record also includes population frequency data and structural context.
R14* (p.Arg14Ter) variant details
- p.Arg14Ter
- rs1362274408
- NCI-TCGA Cosmic COSV5592
- cosmic curated COSV55920
- gnomAD rs1362274408
- Variant assessed as somatic; high impact.
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.846
- CADD 36.00
- UniProt: Variant assessed as somatic; high impact.
- Population evidence available
- Structural context available