R13L (p.Arg13Leu) variant of FBXW7 (Q969H0)
R13L (p.Arg13Leu) in FBXW7 (Q969H0) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
R13L (p.Arg13Leu) variant details
- p.Arg13Leu
- cosmic curated COSV55938
- TOPMed rs1471232420
- gnomAD rs1471232420
- Missense
- Variant Prioritization Score for Impact Estimate 0.508
- REVEL 0.30
- CADD 26.80
- PolyPhen-2 0.93
- SIFT 0.01
- Population evidence available
- Structural context available