G9S (p.Gly9Ser) variant of FBXW7 (Q969H0)
G9S (p.Gly9Ser) in FBXW7 (Q969H0) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
G9S (p.Gly9Ser) variant details
- p.Gly9Ser
- rs1560865017
- NCI-TCGA Cosmic COSV9990
- cosmic curated COSV99900
- Ensembl rs1560865017
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.512
- REVEL 0.31
- CADD 25.70
- PolyPhen-2 0.99
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available