G21D (p.Gly21Asp) variant of FBXW7 (Q969H0)
G21D (p.Gly21Asp) in FBXW7 (Q969H0) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
G21D (p.Gly21Asp) variant details
- p.Gly21Asp
- 1000Genomes rs548137658
- ExAC rs548137658
- TOPMed rs548137658
- gnomAD rs548137658
- Missense
- Variant Prioritization Score for Impact Estimate 0.443
- REVEL 0.23
- CADD 23.30
- PolyPhen-2 0.22
- SIFT 0.00
- Population evidence available
- Structural context available