G21C (p.Gly21Cys) variant of FBXW7 (Q969H0)
G21C (p.Gly21Cys) in FBXW7 (Q969H0) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
G21C (p.Gly21Cys) variant details
- p.Gly21Cys
- cosmic curated COSV10940
- Ensembl rs2126882443
- Missense
- Variant Prioritization Score for Impact Estimate 0.474
- REVEL 0.27
- CADD 24.00
- PolyPhen-2 0.45
- SIFT 0.00
- Population evidence available
- Structural context available