E39K (p.Glu39Lys) variant of FBXW7 (Q969H0)
E39K (p.Glu39Lys) in FBXW7 (Q969H0) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
E39K (p.Glu39Lys) variant details
- p.Glu39Lys
- gnomAD rs1382805117
- Missense
- Variant Prioritization Score for Impact Estimate 0.423
- REVEL 0.19
- CADD 23.80
- PolyPhen-2 0.07
- SIFT 0.00
- Population evidence available
- Structural context available