V23F (p.Val23Phe) variant of FAS (P25445)
V23F (p.Val23Phe) in FAS (P25445) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
V23F (p.Val23Phe) variant details
- p.Val23Phe
- gnomAD 10-89003065-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.235
- CADD 13.90
- PolyPhen-2 0.71
- SIFT 0.20
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available