T13R (p.Thr13Arg) variant of FAS (P25445)
T13R (p.Thr13Arg) in FAS (P25445) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
T13R (p.Thr13Arg) variant details
- p.Thr13Arg
- gnomAD 10-89003036-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.128
- CADD 8.85
- PolyPhen-2 0.61
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available