S32C (p.Ser32Cys) variant of FAS (P25445)
S32C (p.Ser32Cys) in FAS (P25445) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data, published literature, and structural context.
S32C (p.Ser32Cys) variant details
- p.Ser32Cys
- gnomAD 10-89003093-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.559
- CADD 12.50
- PolyPhen-2 0.84
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available