R17S (p.Arg17Ser) variant of FAS (P25445)
R17S (p.Arg17Ser) in FAS (P25445) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
R17S (p.Arg17Ser) variant details
- p.Arg17Ser
- ExAC rs756522969
- gnomAD rs756522969
- Missense
- Variant Prioritization Score for Impact Estimate 0.0847
- CADD 4.49
- PolyPhen-2 0.01
- SIFT 0.08
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available