L52L (p.Leu52Leu) variant of FAS (P25445)
L52L (p.Leu52Leu) in FAS (P25445) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
L52L (p.Leu52Leu) variant details
- p.Leu52Leu
- rs766079591
- gnomAD 10-89003154-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0859
- CADD 0.74
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available