L49M (p.Leu49Met) variant of FAS (P25445)
L49M (p.Leu49Met) in FAS (P25445) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data, published literature, and structural context.
L49M (p.Leu49Met) variant details
- p.Leu49Met
- gnomAD 10-89003143-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.059
- CADD 0.28
- PolyPhen-2 0.48
- SIFT 0.12
- Population evidence available
- Structural context available
- Literature evidence available