L37F (p.Leu37Phe) variant of FAS (P25445)
L37F (p.Leu37Phe) in FAS (P25445) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
L37F (p.Leu37Phe) variant details
- p.Leu37Phe
- gnomAD 10-89003109-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.244
- CADD 15.00
- PolyPhen-2 0.97
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available