L35L (p.Leu35Leu) variant of FAS (P25445)

Name: FAS L35L (p.Leu35Leu) variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-08-21
License: https://catvariant.com/terms-of-use

L35L (p.Leu35Leu) in FAS (P25445) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.

L35L (p.Leu35Leu) variant details

p.Leu35Leu
rs9333296
gnomAD 10-89003101-T-C
Synonymous
Variant Prioritization Score for Impact Estimate 0.0813
CADD 0.09
Most common in the HGDP:LAHU population (allele frequency 0.1)
Structural context available
Cited in: Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American… (PMID 25741868)
Cited in: Analysis of single nucleotide polymorphisms in the FAS and CTLA-4 genes of peripheral T-cell lymphomas. (PMID 19669200)