L18V (p.Leu18Val) variant of FAS (P25445)
L18V (p.Leu18Val) in FAS (P25445) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
L18V (p.Leu18Val) variant details
- p.Leu18Val
- ExAC rs764468017
- gnomAD rs764468017
- Missense
- Variant Prioritization Score for Impact Estimate 0.0674
- CADD 1.43
- PolyPhen-2 0.17
- SIFT 0.21
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available