L12F (p.Leu12Phe) variant of FAS (P25445)
L12F (p.Leu12Phe) in FAS (P25445) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
L12F (p.Leu12Phe) variant details
- p.Leu12Phe
- ExAC rs772912891
- gnomAD rs772912891
- Missense
- Variant Prioritization Score for Impact Estimate 0.0698
- CADD 1.01
- PolyPhen-2 0.01
- SIFT 0.47
- Most common in the South Asian population (allele frequency 8.1e-05)
- Structural context available