K21E (p.Lys21Glu) variant of FAS (P25445)
K21E (p.Lys21Glu) in FAS (P25445) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
K21E (p.Lys21Glu) variant details
- p.Lys21Glu
- gnomAD rs1174183388
- Missense
- Variant Prioritization Score for Impact Estimate 0.234
- CADD 7.92
- PolyPhen-2 0.29
- SIFT 0.23
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available