I4V (p.Ile4Val) variant of FAS (P25445)
I4V (p.Ile4Val) in FAS (P25445) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data, published literature, and structural context.
I4V (p.Ile4Val) variant details
- p.Ile4Val
- gnomAD 10-88990886-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0739
- CADD 2.53
- PolyPhen-2 0.01
- SIFT 0.22
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available