G51C (p.Gly51Cys) variant of FAS (P25445)
G51C (p.Gly51Cys) in FAS (P25445) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data, published literature, and structural context.
G51C (p.Gly51Cys) variant details
- p.Gly51Cys
- gnomAD 10-89003149-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.534
- CADD 22.40
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available