G3A (p.Gly3Ala) variant of FAS (P25445)
G3A (p.Gly3Ala) in FAS (P25445) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
G3A (p.Gly3Ala) variant details
- p.Gly3Ala
- TOPMed rs1223868338
- gnomAD rs1223868338
- Missense
- Variant Prioritization Score for Impact Estimate 0.442
- CADD 8.67
- PolyPhen-2 0.01
- SIFT 0.61
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available