D55Y (p.Asp55Tyr) variant of FAS (P25445)
D55Y (p.Asp55Tyr) in FAS (P25445) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
D55Y (p.Asp55Tyr) variant details
- p.Asp55Tyr
- gnomAD 10-89003161-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.227
- CADD 8.06
- PolyPhen-2 0.04
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available