R15G (p.Arg15Gly) variant of FAN1 (Fanconi-associated nuclease 1)
R15G (p.Arg15Gly) in FAN1 (Fanconi-associated nuclease 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
R15G (p.Arg15Gly) variant details
- p.Arg15Gly
- ExAC rs766836928
- TOPMed rs766836928
- gnomAD rs766836928
- Missense
- Variant Prioritization Score for Impact Estimate 0.414
- REVEL 0.17
- CADD 21.00
- PolyPhen-2 0.15
- SIFT 0.06
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available