P7S (p.Pro7Ser) variant of FAN1 (Fanconi-associated nuclease 1)
P7S (p.Pro7Ser) in FAN1 (Fanconi-associated nuclease 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
P7S (p.Pro7Ser) variant details
- p.Pro7Ser
- TOPMed rs2061930451
- Missense
- Variant Prioritization Score for Impact Estimate 0.0934
- REVEL 0.09
- CADD 0.18
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available