N22T (p.Asn22Thr) variant of FAN1 (Fanconi-associated nuclease 1)
N22T (p.Asn22Thr) in FAN1 (Fanconi-associated nuclease 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
N22T (p.Asn22Thr) variant details
- p.Asn22Thr
- ExAC rs764729330
- gnomAD rs764729330
- Missense
- Variant Prioritization Score for Impact Estimate 0.155
- REVEL 0.09
- CADD 8.99
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available