K25S (p.Lys25Ser) variant of FAN1 (Fanconi-associated nuclease 1)
K25S (p.Lys25Ser) in FAN1 (Fanconi-associated nuclease 1) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
K25S (p.Lys25Ser) variant details
- p.Lys25Ser
- rs750426078
- gnomAD 15-30904732-GAA-G
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.264
- CADD 25.90
- Population evidence available
- Structural context available
- Literature evidence available