K23R (p.Lys23Arg) variant of FAN1 (Fanconi-associated nuclease 1)
K23R (p.Lys23Arg) in FAN1 (Fanconi-associated nuclease 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
K23R (p.Lys23Arg) variant details
- p.Lys23Arg
- Ensembl rs2061932661
- Missense
- Variant Prioritization Score for Impact Estimate 0.13
- REVEL 0.05
- CADD 16.00
- PolyPhen-2 0.01
- SIFT 0.14
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available