K21K (p.Lys21Lys) variant of FAN1 (Fanconi-associated nuclease 1)
K21K (p.Lys21Lys) in FAN1 (Fanconi-associated nuclease 1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
K21K (p.Lys21Lys) variant details
- p.Lys21Lys
- rs756748584
- gnomAD 15-30904726-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.378
- CADD 7.90
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available
- Literature evidence available