K11G (p.Lys11Gly) variant of FAN1 (Fanconi-associated nuclease 1)
K11G (p.Lys11Gly) in FAN1 (Fanconi-associated nuclease 1) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
K11G (p.Lys11Gly) variant details
- p.Lys11Gly
- rs752820596
- gnomAD 15-30904690-CAAAA
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.269
- CADD 26.60
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available
- Literature evidence available